Enzyme Q10: Why Pharma Marketing Companies must have it in Their Product Portfolio
Key points:
- Q10 is a widely used in cosmetics, food products and brewages industry
- It is helpful in the treatment of various health issues like cardiovascular events, diabetes, infertility, liver etc.
- As the awareness increased regarding coenzyme Q10 among the consumers, it raises the demand of Q10 in the global market
- Q10 is recognized as a powerful anti-ageing ingredient and extensively used in anti-ageing creams and sunscreen lotion
- A steep consumption of Q10 as nutritional supplements in daily routine expand the Q10 market size.
The antioxidant market is a booming market nowadays. Almost all pharmaceutical and biotech companies are focused in manufacturing antioxidants and gaining huge profits. Various type of antioxidants is available in the market for different medical conditions. Enzyme Q10 is the most prevalent amongst all of them. Q10 is a nutrient that is naturally found in the body as well as in the different type of foods also. It plays an essential role in the metabolism and protects the cell from damage. Coenzyme Q10 is also known as uniquinone, ubidecarenone and coenzyme Q. It is a 1-4 benzoquinone, where Q refers to the quinine chemical group and 10 refers to the number of isoprenyl chemical subunits. Fat-soluble substance, which resembles a vitamin, is present in all respiring eukaryotic cells, primarily in the mitochondria.
Enzyme Q10 is discovered by Fedrick L. Crane in 1957. Its chemical structure was reported by Karl Folkers. A British scientist Peter Mitchell got the noble prize in 1978 for excellent work in the development of Q10. The Biomedical communities have gathered an extensive knowledge base about the absorption, safety and health effects of Co-enzyme Q10. CoQ10 is used to treat several medical conditions like lowering of blood pressure, reducing the cardiac risks when combined with regular medication. CoQ10 may help to prevent or treat the adverse effects of taking statin-type cholesterol drugs such as muscle pains and liver problems,. Enzyme Q10 is also used in the preventive treatment for low sperm count, HIV, Cancer, Muscular dystrophy and migraine.
Effect of CoQ10 in cardiovascular diseases:
Cardiovascular disorders are the major cause of morbidity and mortality. There are several factors which lead to the heart failure or other heart problems. CoQ10 is present in the all parts of the body. The healthy range of CoQ10 is 0.68µmol/l – 1.1µmol/l. Heart, skeletal muscles, liver and kidney have the highest amount of the enzyme CoQ10. In various clinical studies, there is the deficiency of CoQ10 which has been noted in cardiovascular diseases. Moreover, the clinical benefits of supplementation of Q10 in cardiovascular disorders have been found in several clinical studies. CoQ10 is beneficial for the nourishment of the heart. Enzyme Q10 improve the cardiovascular disorders by following mechanisms
- Improvement of cardiac bioenergetics
- Free radical scavenging action or antioxidant action
- Amelioration of endothelial function and vasodilatation
- Depletion in pro inflammatory cytokines
- Membrane stabilization action
Effect of CoQ10 in diabetes:
Diabetes is the second most common metabolic disorder. In several cases, reduction of the antioxidant level is also found in the body of a diabetic patient. Enzyme Q10 is a potent antioxidant. It depletes the free radicals from the body which plays a very significant role in the treatment of diabetic neuropathy. Supplementation of CoQ10 also affects the other biomarkers of diabetes like steep reduction in Glycated hemoglobin, decrease in serum cholesterol, serum triglyceride levels and an increase in HDL levels. Coenzyme Q10 treatment also reduces lipid per oxidation.
Effect of CoQ10 on liver
The oxidative stress is the key factor responsible for the liver dysfunction. CoQ10 is the foremost component of the mitochondrial respiratory chain. It has been found that a reduced level of CoQ10 in plasma is one of the markers in mitochondrial dysfunction in non alcoholic fatty acid liver disease.
Effect of CoQ10 in infertility:
Infertility is the reproductive disorder which becomes a major cause of distress among the males. Excessive production of reactive oxygen species causes the reduction of sperm motility and amount which leads to the reduction in sperm mitochondrial adenosine triphosphate (ATP) production, resulting in male infertility. The supplementation of CoQ10 increases Q10 levels in semen and can be effective in improving sperm kinetic features in patients affected by idiopathic asthenozoospermia.
Effect of CoQ10 in Periodontal disease:
The level of CoQ10 in the body is reduced in gingiva with the age, and the risk of periodontal disease is increases. The Deficiency of CoQ 10 was found in human inflamed gingiva and has been found to be responsible for the periodontal destruction. It has been noted in several studies that the antioxidant action of CoQ10 have the positive results in the treatment of periodontal disease.
Why must Pharma Marketing Companies have it in their Product Portfolio?
As the awareness increased regarding coenzyme Q10 among the consumers, it raises the demand of Q10 in the global market. The inherent benefits of Q10 in the treatment of cancer and Huntington disease has also contributed towards market growth. Its extensive utilization in the treatment of cardiovascular diseases, cognitive illness and in periodontal diseases elevates its demand in the market.
Q10 is the widely used in the anti-aging formulations. According to the United nation report in 2013, the age rate became 11.1% to 19.6% from 2010 to 2040. An increase in aging population in U.S, Japan, U.K and Russia has created a huge demand of anti-aging creams. Q10 is recognized as a powerful anti-aging ingredient and extensively used in anti-aging creams and sunscreen lotions. It is also responsible for the generation of biological energy required to stimulate skin repair. The increasing rate of pollution and growing concern regarding the UV effect on the skin will surely increase the Q10 demands in the future.
According to studies conducted by life extension foundation, it has been approved that Q10 is capable in inhibiting the growth of PC3 cancer cells when given along with conventional cancer treatment. It has been found that daily dosage of 390 mg along with conventional treatment therapy has reduced the tumor size and retracing metastasis. The patients showed up to 44% reduction in degeneration of motor skills, movement of mental function as compared to the patient who did not consumed it.
A steep consumption of Q10 as nutritional supplements in daily routine expand the Q10 market size. Most of the food companies use enzyme Q10 as an ingredient in energy drinks and the functional food due to its antioxidant properties.
With the increasing demand in the market and having multiple uses in various diseases makes Q10 a product of huge sales potential. .CoQ10 is kind of a product which every Pharma marketing company should definitely have in their portfolio.
https://www.transparencymarketresearch.com/coenzyme-q10-market.html
https://www.marketresearchstore.com/news/coenzyme-q10-market-138
https://www.webmd.com/diet/supplement-guide-coenzymeq10-coq10#1
https://en.wikipedia.org/wiki/Coenzyme_Q10
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991687/
https://www.grandviewresearch.com/industry-analysis/coenzyme-q10-coq10-market
https://www.gminsights.com/industry-analysis/coenzyme-q10-coq10-market
https://www.fda.gov/downloads/drugs/developmentapprovalprocess/manufacturing/ucm334583.pdf
https://pdfs.semanticscholar.org/13ce/21d9733b78dcdb6242b72adf8a6a926e69e1.pdf
https://bjd-abcd.com/index.php/bjd/article/viewFile/251/442
Recent Comments